Tag Archives: biotechnology

The Future of Biotechnology – Guiding Change to Advance Science

Advances in science, new actors, economic investments, and societal challenges and concerns will all influence new types of biotechnology products in development. These publications explore possibilities, obstacles, and societal considerations as we experience changes in the scope, scale, complexity, and tempo of biotechnology products. All are free to read or download.

Safeguarding the Bioeconomy

Research and innovation in the life sciences is driving rapid growth in agriculture, biomedical science, information science and computing, energy, and other sectors of the U.S. economy. This economic activity, conceptually referred to as the …

[more]

Forest Health and Biotechnology: Possibilities and Considerations

The American chestnut, whitebark pine, and several species of ash in the eastern United States are just a few of the North American tree species that have been functionally lost or are in jeopardy of being lost due to outbreaks of pathogens and …

[more]

The Next Generation of Biomedical and Behavioral Sciences Researchers: Breaking Through

Since the end of the Second World War, the United States has developed the world’s preeminent system for biomedical research, one that has given rise to revolutionary medical advances as well as a dynamic and innovative business sector …

[more]

Biodefense in the Age of Synthetic Biology

Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and …

[more]

Preparing for Future Products of Biotechnology

Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of …

[more]

Dual Use Research of Concern in the Life Sciences: Current Issues and Controversies

The potential misuse of advances in life sciences research is raising concerns about national security threats. Dual Use Research of Concern in the Life Sciences: Current Issues and Controversies examines the U.S. strategy for reducing …

[more]

Genetically Engineered Crops: Experiences and Prospects

Genetically engineered (GE) crops were first introduced commercially in the 1990s. After two decades of production, some groups and individuals remain critical of the technology based on their concerns about possible adverse effects on human …

[more]

Gene Drives on the Horizon: Advancing Science, Navigating Uncertainty, and Aligning Research with Public Values

Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as …

[more]

Industrialization of Biology: A Roadmap to Accelerate the Advanced Manufacturing of Chemicals

The tremendous progress in biology over the last half century – from Watson and Crick’s elucidation of the structure of DNA to today’s astonishing, rapid progress in the field of synthetic biology – has positioned us for significant innovation in …

[more]

Positioning Synthetic Biology to Meet the Challenges of the 21st Century: Summary Report of a Six Academies Symposium Series

Synthetic biology — unlike any research discipline that precedes it — has the potential to bypass the less predictable process of evolution to usher in a new and dynamic way of working with living systems. Ultimately, synthetic biologists hope …

[more]

Convergence: Facilitating Transdisciplinary Integration of Life Sciences, Physical Sciences, Engineering, and Beyond

Convergence of the life sciences with fields including physical, chemical, mathematical, computational, engineering, and social sciences is a key strategy to tackle complex challenges and achieve new and innovative solutions. However, …

[more]

Human Gene Editing: The Issues Behind the Progress in Genetics

gene_169470

A major component of the National Academy of Sciences and the National Academy of Medicine’s Human Gene-Editing Initiative was the International Summit on Human Gene Editing that took place this past week. Co-hosted with the Chinese Academy of Sciences and the U.K.’s Royal Society, the summit convened experts from around the world to discuss the scientific, ethical, and governance issues associated with human gene-editing research. The Summit Statement is available here, and the video and slides of the Summit will be permanently available at the summit website.

Below is a list of our titles that were either directly mentioned in presentations, or are related to this topic. All are free to download.

2008 Amendments to the National Academies’ Guidelines for Human Embryonic Stem Cell Research (2008)


ISBN 978-0-309-12220-7

In 2005, the National Academies released the report Guidelines for Human Embryonic Stem Cell Research, which offered a common set of ethical standards for a field that, due to the absence of comprehensive federal funding, was lacking national …

[more]

Potential Risks and Benefits of Gain-of-Function Research: Summary of a Workshop (2015)


ISBN 978-0-309-36783-7

On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called …

[more]

Biotechnology Research in an Age of Terrorism (2004)


ISBN 978-0-309-08977-7

In recent years much has happened to justify an examination of biological research in light of national security concerns. The destructive application of biotechnology research includes activities such as spreading common pathogens or …

[more]

Globalization, Biosecurity, and the Future of the Life Sciences (2006)


ISBN 978-0-309-10032-8

Biomedical advances have made it possible to identify and manipulate features of living organisms in useful ways&#8212leading to improvements in public health, agriculture, and other areas. The globalization of scientific and technical expertise …

[more]

Improving the Efficiency and Effectiveness of Genomic Science Translation: Workshop Summary (2014)


ISBN 978-0-309-29453-9

The process for translating basic science discoveries into clinical applications has historically involved a linear and lengthy progression from initial discovery to preclinical testing, regulatory evaluation and approval, and, finally, use in …

[more]

Conflict of Interest and Medical Innovation: Ensuring Integrity While Facilitating Innovation in Medical Research: Workshop Summary (2014)


ISBN 978-0-309-30168-8

Scientific advances such as the sequencing of the human genome have created great promise for improving human health by providing a greater understanding of disease biology and enabling the development of new drugs, diagnostics, and preventive …

[more]

A Survey of Attitudes and Actions on Dual Use Research in the Life Sciences: A Collaborative Effort of the National Research Council and the American Association for the Advancement of Science (2009)


ISBN 978-0-309-12510-9

The same technologies that fuel scientific advances also pose potential risks–that the knowledge, tools, and techniques gained through legitimate biotechnology research could be misused to create biological weapons or for bioterrorism. This is …

[more]

Challenges and Opportunities for Education About Dual Use Issues in the Life Sciences (2010)


ISBN 978-0-309-15840-4

The Challenges and Opportunities for Education About Dual Use Issues in the Life Sciences workshop was held to engage the life sciences community on the particular security issues related to research with dual use potential. More than 60 …

[more]

Diplomacy for the 21st Century: Embedding a Culture of Science and Technology Throughout the Department of State (2015)


ISBN 978-0-309-37313-5

Diplomacy for the 21st Century recommends steps that the Department of State should embrace to take full advantage of the leading science and technology (S&T) capabilities of the United States. These capabilities provide the department …

[more]

Public Engagement on Genetically Modified Organisms: When Science and Citizens Connect: A Workshop Summary (2015)


ISBN 978-0-309-37421-7

The National Research Council’s Roundtable on Public Interfaces of the Life Sciences held a 2-day workshop on January 15-16, 2015, in Washington, DC to explore the public interfaces between scientists and citizens in the context of genetically …

[more]

Trust and Confidence at the Interfaces of the Life Sciences and Society: Does the Public Trust Science? A Workshop Summary (2015)


ISBN 978-0-309-37792-8

Does the public trust science? Scientists? Scientific organizations? What roles do trust and the lack of trust play in public debates about how science can be used to address such societal concerns as childhood vaccination, cancer screening, and …

[more]

Improving Genetics Education in Graduate and Continuing Health Professional Education: Workshop Summary (2015)


ISBN 978-0-309-31605-7

Many health care providers do not have either the knowledge or the tools they need in order to apply genetic information in their day-to-day practices. This lack of support is contributing to a substantial delay in the translation of genetic …

[more]

The Value of Genetic and Genomic Technologies: Workshop Summary (2010)


ISBN 978-0-309-15771-1

Knowing one’s genetic disposition to a variety of diseases, including common chronic diseases, can benefit both the individual and society at large. The IOM’s Roundtable on Translating Genomic-Based Research for Health held a workshop on March …

[more]

Genomics-Enabled Learning Health Care Systems: Gathering and Using Genomic Information to Improve Patient Care and Research: Workshop Summary (2015)


ISBN 978-0-309-37112-4

The inclusion of genomic data in a knowledge-generating health care system infrastructure is one promising way to harness the full potential of that information to provide better patient care. In such a system, clinical practice and research …

[more]

Assessing Genomic Sequencing Information for Health Care Decision Making: Workshop Summary (2014)


ISBN 978-0-309-30494-8

Rapid advances in technology have lowered the cost of sequencing an individual’s genome from the several billion dollars that it cost a decade ago to just a few thousand dollars today and have correspondingly greatly expanded the use of genomic …

[more]

Integrating Large-Scale Genomic Information into Clinical Practice: Workshop Summary (2012)


ISBN 978-0-309-22034-7

The initial sequencing of the human genome, carried out by an international group of experts, took 13 years and $2.7 billion to complete. In the decade since that achievement, sequencing technology has evolved at such a rapid pace that today a …

[more]

Assessing Genetic Risks: Implications for Health and Social Policy (1994)


ISBN 978-0-309-08660-8

Raising hopes for disease treatment and prevention, but also the specter of discrimination and “designer genes,” genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of …

[more]

Emerging and Readily Available Technologies and National Security: A Framework for Addressing Ethical, Legal, and Societal Issues (2014)


ISBN 978-0-309-29334-1

Emerging and Readily Available Technologies and National Security is a study on the ethical, legal, and societal issues relating to the research on, development of, and use of rapidly changing technologies with low barriers of entry that …

[more]

The Dual Use Dilemma: Biological Research and Security in an Age of Terrorism

The great achievements of molecular biology and genetics over the last 50 years have produced advances in agriculture and industrial processes and have revolutionized the practice of medicine. The very technologies that fueled these benefits to society, however, pose a potential risk as well—the possibility that these technologies could also be used to create the next generation of biological weapons. Biotechnology represents a “dual use” dilemma in which the same technologies can be used legitimately for human betterment and misused for bioterrorism.

The Institute of Medicine and the National Research Council have produced a number of reports on the subject of bioterrorism and dual use issues in life science research. All are free to download.

Biotechnology Research in an Age of Terrorism

Download Free PDF

Biotechnology Research in an Age of Terrorism
164 pages | Paperback | Price: $31.50
In recent years much has happened to justify an examination of biological research in light of national security concerns. The destructive application of biotechnology research includes activities such as spreading common pathogens or transforming them…[more]
Challenges and Opportunities for Education About Dual Use Issues in the Life Sciences

Download Free PDF

Challenges and Opportunities for Education About Dual Use Issues in the Life Sciences
146 pages | Paperback | Price: $22.50The Challenges and Opportunities for Education About Dual Use Issues in the Life Sciences workshop was held to engage the life sciences community on the particular security issues related to research with dual use potential. More than 60 participants from… [more]
A Survey of Attitudes and Actions on Dual Use Research in the Life Sciences

Download Free PDF

A Survey of Attitudes and Actions on Dual Use Research in the Life Sciences: A Collaborative Effort of the National Research Council and the American Association for the Advancement of Science
188 pages | Paperback | Price: $78.30 The same technologies that fuel scientific advances also pose potential risks–that the knowledge, tools, and techniques gained through legitimate biotechnology research could be misused to create biological weapons or for bioterrorism. This is often called… [more]
Globalization, Biosecurity, and the Future of the Life Sciences

Download Free PDF

Globalization, Biosecurity, and the Future of the Life Sciences
318 pages | Paperback | Price: $50.40
Biomedical advances have made it possible to identify and manipulate features of living organisms in useful ways&#8212leading to improvements in public health, agriculture, and other areas. The globalization of scientific and technical expertise also means that… [more]

 

Biological Threats and Terrorism

Download Free PDF

Biological Threats and Terrorism: Assessing the Science and Response Capabilities: Workshop Summary
336 pages | Paperback | Price: $37.80 In the wake of September 11th and recent anthrax events, our nation?s bioterrorism response capability has become an imminent priority for policymakers, researchers, public health officials, academia, and the private sector. In a three-day workshop, convened by.. .[more]