Tag Archives: clinical research

Sharing Clinical Trial Data to Advance Scientific Discovery and Improve Care

Clinical trials generate vast amounts of data, yet a large portion of this information is never published or made available to other researchers. Data sharing could advance scientific discovery and improve clinical care, but it involves potential risks and costs for key stakeholders, including clinical trialists, sponsors, researchers, and patients. Our publications discuss the challenges and opportunities for stakeholders to better harmonize incentives, policy, data standards, and governance to encourage the sharing and reuse of clinical trial data sharing.

Sharing Clinical Trial Data: Maximizing Benefits, Minimizing Risk

Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and …

	Examination of Front-of-Package Nutrition Rating Systems and Symbols: Phase I Report The federal government requires that most packaged foods carry a standardized label–the Nutrition Facts panel–that provides nutrition information intended to help consumers make healthful choices. In recent years, manufacturers have begun to include…
	The Power of Renewables: Opportunities and Challenges for China and the United States The United States and China are the world’s top two energy consumers and, as of 2010, the two largest economies. Consequently, they have a decisive role to play in the world’s clean energy future. Both countries are also motivated by related goals, namely…
	High School Dropout, Graduation, and Completion Rates: Better Data, Better Measures, Better Decisions High school graduation and dropout rates have long been used as indicators of educational system productivity and effectiveness and of social and economic well being. While determining these rates may seem like a straightforward task, their calculation is in…
	The Role of Human Factors in Home Health Care: Workshop Summary The rapid growth of home health care has raised many unsolved issues and will have consequences that are far too broad for any one group to analyze in their entirety. Yet a major influence on the safety, quality, and effectiveness of home health care will be…
	Strengthening the National Institute of Justice The National Institute of Justice (NIJ) is the nation’s primary resource for advancing scientific research, development, and evaluation on crime and crime control and the administration of justice in the United States. Headed by a presidentially appointed…
	The 2009 H1N1 Influenza Vaccination Campaign: Summary of a Workshop Series The 2009 H1N1 vaccination campaign was one of the largest public health campaigns in U.S. history, vaccinating one-quarter of the population in the first three months. The IOM held three workshops in Raleigh, NC; Austin, TX; and Seattle, WA to learn from…
	When Weather Matters: Science and Service to Meet Critical Societal Needs The past 15 years have seen marked progress in observing, understanding, and predicting weather. At the same time, the United States has failed to match or surpass progress in operational numerical weather prediction achieved by other nations and failed to…
	Research Priorities for Assessing Health Effects from the Gulf of Mexico Oil Spill: A Letter Report It is as yet uncertain how the Gulf of Mexico oil spill will affect the health of clean-up workers and volunteers, residents, and visitors in the Gulf. The IOM recommends that the U.S. Department of Health and Human Services focus on researching psychological…
	Transforming Clinical Research in the United States: Challenges and Opportunities: Workshop Summary An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and…
	Critical Code: Software Producibility for Defense Critical Code contemplates Department of Defense (DoD) needs and priorities for software research and suggests a research agenda and related actions. Building on two prior books–Summary of a Workshop on Software Intensive Systems and…